KICK [<channel>] <nicks> [<reason>]
The channel and the nicknames, separated by a comma, to kick from the channel and the reason thereof; if no channel is given, the active channel will be used.
Removes the given nicknames from the specified channel; this command is typically used to remove troublemakers, flooders or people otherwise making a nuisance of themselves.
/KICK mike Please... chill down! /KICK #irssi bob,sarah Stop flooding!